Abstract
In this paper the benefits of the oxidative properties of PIFA –one of the most generally employed hypervalent iodine reagents oriented to the preparation of a number of pyrrolidine heterocycles from properly substituted amides will be disclosed. The intramolecular reaction of the resultant electrophilic N-acylnitrenium intermediate with an olefin or alkyne fragment will facilitate the formation of the required C–N connection. The absence of any metal source in the I(III)-mediated olefin- or alkyne- intramolecular amidation step, and the structural versatility of the final heterocycles that are prepared, feature the present methodology.