Abstract
Palladium-catalyzed cross-coupling reactions are fundamental organometallic transformations and nowadays have become a principal method of forming carbon-carbon and carbon-heteroatom bonds. In this report, essential features of cross-coupling reactions are review, mainly focused in the less developed C-S bond forming process. In addition, the results obtained in the coupling of aryl halides with aliphatic and aromatic thiols using a catalyst system derived from the bisphosphine Josiphos CyPFtBu ligand are presented.