Arylation reactions with aryldiazonium salts catalysed by gold

Abstract

In recent years, various protocols that facilitate the oxidation of homogeneous Au(I) catalysts have emerged. The latter has allowed the exploration of the synthetic potential associated with the implementation of Au(I)/Au(III) redox cycles. In this context, our research group has contributed to the development of gold-mediated or -catalysed methodologies that enable the formation of C(S)-aryl bonds, utilizing aryldiazonium salts as electrophiles. This article summarizes the state of the art of research in this area and our contribution to it. Furthermore, it reveals a less-explored type of reactivity in which aryldiazonium salts retain the diazo group, resulting in nitrogen heterocyclic compounds.