Keywords
biomolecular condensates
coacervates
supramolecular chemistry
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Abstract
Emulating biological life in synthetic cells has gained widespread attention over the past decade. The discovery of liquid-like organelles in 2009, widely known as biomolecular condensates, has made a paradigm shift in the field of cellular and molecular biology. In response, chemists have developed simplified synthetic analogues for these membraneless liquid-like condensates, named coacervates. Here, we highlight how coacervates serve as ideal empirical models for studying structure-function relationships and in un-derstanding complex cellular machinery.
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