Resumen
Los sistemas compuestos basados en nanopartículas plasmónicas (PNPs) y en redes metal-orgánicas (MOFs, por sus siglas en inglés Metal-Organic Frameworks) presentan un gran potencial en diversos campos (ej. biomedicina, detección, (foto)catálisis). En biomedicina, estos nanocomposites se han posicionado como plataformas muy prometedoras para terapias oncológicas. La combinación de elevada porosidad y versatilidad química y estructural de los MOFs con las excelentes propiedades ópticas de las PNPs ha permitido obtener nanomateriales multifuncionales capaces de integrar una eficiente terapia y diagnóstico en una única nanomedicina, resultando en herramientas teranósticas.
Esta revisión bibliográfica presenta los avances más recientes en el desarrollo de nanoplataformas PNP@MOF, abordando las diferentes estrategias de preparación y analizando sus aplicaciones más relevantes en biomedicina, con especial atención a los sistemas multimodales capaces de integrar funciones terapéuticas y técnicas de bioimagen.
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