Abstract
The first floor of the building of the Institute of Chemistry of the Escuela Nacional de Ciencias Químicas was inaugurated on April 4, 1941. It was sponsored by El Colegio de México as a result of the initiative of Alfonso Reyes and Daniel Cosío. Dr. Antonio Madinaveitia, its Spanish director, had established natural products as a line research. On July 25, 1939, the first budget for research was spent on well-established work plans and on the line of research that continues to be studied until now. It is relevant to appreciate the role played by Antonio Madinaveitia, Alfonso Reyes and Daniel Cosío in their founding.